Using data envelopment analysis to defuzzify a group of dependent fuzzy numbers

The defuzzification process converts fuzzy numbers to crisp ones and is an important stage in the implementation of fuzzy systems. In many actual applications, relationships among data indicate their mathematical dependence on one another. Hence, this study proposes a new method based on the Data Envelopment Analysis (DEA) model to defuzzify a group of dependent fuzzy numbers. It also aims to obtain the crisp points that satisfy the characteristics of these data as a group by approximating the optimal solutions within the production possibility set of the DEA model.The proposed method partitions the fuzzy numbers, and the relationships among these numbers are observed as constraints. Finally, the usefulness of this new method is illustrated in a real-world problem

Patient Safety Culture and Nursing Shortage among Nurses in Al-Medina Hospitals

This article explores the current relationship of patient safety culture to the nursing shortage in general hospitals in the city of Al-Medina, Saudi Arabia. A mixed methods article was conducted on 335 respondents drawn from 10 government hospitals in the region. We utilized an AHRQ Questionnaire for data collection, and we analyzed the data with statistical approaches such as the mean, percentages, and standard deviation. This analysis established significant relationship between patient safety cultures and nursing shortages. Furthermore, we found a weak and positive relationship between some of patient SC’s components and nursing shortages in the hospitals studied; these components included communications (r=0.144, p<0.05), the frequency of event reports (r=0.151, p<0.05), and hospital work area (r=0.329, p<0.05). Most of the nurses who participated in the current article had low incident report rates, with only three to five event reports in one year. However, among the dimensions of patient safety culture, it was found in this article that the nurses had a high level of communication (3.91±0.54/High). The overall grading of patient safety culture was moderate (3.27±0.93) in Al-Medina City. The findings of this investigation will help the Ministry of Health (MOH) decide how to improve patient safety. Moreover, to increase the condition of nursing care provided to the patients and to boost patient safety culture, the healthcare sector must consider the factors and other causes. It is also crucial that nurse leaders learn to maintain and secure patient safety and that nurses learn to frequently report incidents, including any actual errors. Keywords: Patient Safety, Culture, Nursing Shortage DOI: 10.7176/JHMN/100-07 Publication date:May 31st 202

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility and 19 for COVID-19 disease severity. Four of these 23 loci likely have an ethnicity-specific component. Genome-wide association study (GWAS) signals in 11 loci colocalize with expression quantitative trait loci (eQTLs) associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene), including lung, brain, heart, muscle, and skin as well as the digestive system and immune system. We perform genetic fine mapping to compute 99% credible SNP sets, which identify 10 GWAS loci that have eight or fewer SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome, affecting gene expression levels in a wide variety of tissue types

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic

A first update on mapping the human genetic architecture of COVID-19

peer reviewe

A Case of Cystic Arrhenoblastoma of the Ovary

The authors have observed one patient whose vision has slowly been lessened. They :have written all the ophthalmoscopic changes which would help in diagnosis of a angioid strire of the retina. The patient showed some skin lesions as well, which proved the existence of a general affection. At the end, the authors have written all the associated forms ofm the disease and other familial and mesodermic affections which may be seen with it

A multinational Delphi consensus to end the COVID-19 public health threat

Despite notable scientific and medical advances, broader political, socioeconomic, and behavioural factors continue to undercut the response to the coronavirus disease 2019 (COVID-19) pandemic1,2. This Delphi study convened a diverse, multidisciplinary panel of 386 academic, health, NGO, government and other experts in COVID-19 response from 112 countries and territories to recommend specific actions to end this persistent global public health threat. The panel developed a set of 41 consensus statements and 57 recommendations to governments, health systems, industry, and other key stakeholders across six domains: communication; health systems; vaccination; prevention; treatment and care; and inequities. In the wake of nearly three years of ragmented global and national responses, it is instructive to note that three of the highest-ranked recommendations call for the adoption of whole-of-society and whole-of-government approaches1, while maintaining proven prevention measures using a vaccines-plus approach2 that employs a range of public health and financial support measures to complement vaccination. Other recommendations with at least 99% combined agreement advise governments and other stakeholders to improve communication, rebuild public trust, and engage communities3 in the management of pandemic responses. The findings of the study, which have been further endorsed by organisations globally, include points of unanimous agreement, as well as six recommendations with >5% disagreement, that provide health and social policy actions to address inadequacies in the pandemic response and help bring this public health threat to an end

A multinational Delphi consensus to end the COVID-19 public health threat

Abstract Despite notable scientific and medical advances, broader political, socioeconomic and behavioural factors continue to undercut the response to the COVID-19 pandemic . Here we convened, as part of this Delphi study, a diverse, multidisciplinary panel of 386 academic, health, non-governmental organization, government and other experts in COVID-19 response from 112 countries and territories to recommend specific actions to end this persistent global threat to public health. The panel developed a set of 41 consensus statements and 57 recommendations to governments, health systems, industry and other key stakeholders across six domains: communication; health systems; vaccination; prevention; treatment and care; and inequities. In the wake of nearly three years of fragmented global and national responses, it is instructive to note that three of the highest-ranked recommendations call for the adoption of whole-of-society and whole-of-government approaches , while maintaining proven prevention measures using a vaccines-plus approach that employs a range of public health and financial support measures to complement vaccination. Other recommendations with at least 99% combined agreement advise governments and other stakeholders to improve communication, rebuild public trust and engage communities in the management of pandemic responses. The findings of the study, which have been further endorsed by 184 organizations globally, include points of unanimous agreement, as well as six recommendations with >5% disagreement, that provide health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end